Author's response to reviews Title: Treatment Use in Prognostic Model Research: a Systematic Review of Cardiovascular Prognostic Studies Authors:

Title: Treatment Use in Prognostic Model Research: a Systematic Review of Cardiovascular Prognostic Studies Authors: Romin Pajouheshnia ([email protected]) Johanna Damen ([email protected]) Rolf Groenwold ([email protected]) Karel Moons ([email protected]) Linda Peelen ([email protected]) Version: 1 Date: 01 Sep 2017 Author’s response to reviews: Dear Dr Snell, We would like to thank you for your consideration and evaluation of our manuscript, “Treatment Use in Prognostic Model Research: a Systematic Review”. We would like to thank the reviewers for the comments and suggestions provided. The feedback was thorough and informative, and has provided the basis for necessary improvements to the original manuscript. We have addressed all comments and suggestions provided by the reviewers. Changes have been made using “track changes” as requested, and we submit a revised manuscript with revised figures (where necessary) alongside this letter. We hope that the outlined adjustments to the manuscript are sufficient in clarifying your concerns, and we would again like to thank you for your suggested revisions.